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Jane C. Wright compared patients' responses with tests on their cultured tumour tissue, helping turn chemotherapy from a last gamble into a systematic field of cancer medicine.

Jane C. Wright lets the tumour answer

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Why it matters

The idea in context

At Harlem Hospital's Cancer Research Foundation, Wright and her father Louis grew samples of human tumours and exposed them to candidate drugs, then compared the laboratory response with what happened in the patient. She went on to investigate drug combinations, build a cross-referenced record of cancers and treatments, and develop catheter techniques for delivering potent agents to deep tumours. In a discipline still proving that medicines could treat cancer at all, she made response something to observe, compare and learn from.

Türkçe

Aynı kart, başka bir dilde.

Jane C. Wright, hastaların verdiği yanıtları kültürde çoğaltılan tümör dokusu üzerindeki testlerle karşılaştırdı; kemoterapinin son bir kumardan sistemli bir kanser tıbbı alanına dönüşmesine yardım etti.
Jane C. Wright tümörün yanıtını dinliyor

Wright, Harlem Hospital Cancer Research Foundation'da babası Louis ile insan tümörlerinden alınan örnekleri çoğaltıp aday ilaçlara maruz bıraktı; laboratuvardaki yanıtı hastada olanlarla karşılaştırdı. Daha sonra ilaç kombinasyonlarını araştırdı, kanser türleriyle tedavileri çapraz eşleştiren bir kayıt sistemi kurdu ve güçlü maddeleri derindeki tümörlere ulaştıran kateter teknikleri geliştirdi. İlaçların kanseri gerçekten tedavi edebileceğini henüz kanıtlamaya çalışan bir alanda, yanıtı gözlemlenecek, karşılaştırılacak ve öğrenilecek bir şeye dönüştürdü.

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Background reading: Jane C. WrightAttribution and context are revised when stronger evidence appears. Corrections are welcome through the editorial page.
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